Two Models for Multiple Sclerosis: Experimental Allergic Encephalomyelitis and Theilerʼs Murine Encephalomyelitis Virus
نویسندگان
چکیده
منابع مشابه
Experimental allergic encephalomyelitis: a misleading model of multiple sclerosis.
Despite many years of intensive research, multiple sclerosis (MS) defies understanding and treatment remains suboptimal. The prevailing hypothesis is that MS is immune mediated and that experimental allergic encephalomyelitis (EAE) is a suitable model to elucidate pathogenesis and devise therapy. This review examines critically the validity that EAE is an adequate and useful animal model of MS ...
متن کامل"induction of experimental allergic encephalomyelitis in c57/bl6 mice:an animal model for multiple sclerosis "
basic research on the autoimmune disease multiple sclerosis has been performed mainly on its animal model namely experimental allergic encephalomyelitis. there are many different approaches established to get this model. despite the existence of many references in literature in this regard, we have been faced with many difficulties generating the model suitable for studying different therapies....
متن کاملEffect of Honey Bee Venom on Lewis Rats with Experimental Allergic Encephalomyelitis, a Model for Multiple Sclerosis
Multiple sclerosis (MS) is a progressive and autoimmune neurodegenerative disease of the central nervous system (CNS). This disease is recognized through symptoms like inflammation, demyelination and the destruction of neurological actions. Experimental allergic encephalomyelitis (EAE) is a widely accepted animal model for MS. EAE is created in animals by injecting the tissue of myelin basic...
متن کاملEffect of Honey Bee Venom on Lewis Rats with Experimental Allergic Encephalomyelitis, a Model for Multiple Sclerosis
Multiple sclerosis (MS) is a progressive and autoimmune neurodegenerative disease of the central nervous system (CNS). This disease is recognized through symptoms like inflammation, demyelination and the destruction of neurological actions. Experimental allergic encephalomyelitis (EAE) is a widely accepted animal model for MS. EAE is created in animals by injecting the tissue of myelin basic...
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Experimental allergic encephalomyelitis (EAE)' is an autoimmune disease of the central nervous system (CNS) that is induced by immunization of susceptible animal strains with myelin basic protein (MBP). The disease is characterized by lymphocyte infiltration leading to CNS lesions, demyelination, and chronic relapsing paralysis, which are symptoms similar to those seen for multiple sclerosis (M...
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ژورنال
عنوان ژورنال: Journal of Neuropathology and Experimental Neurology
سال: 1996
ISSN: 0022-3069
DOI: 10.1097/00005072-199606000-00001